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Chitin synthase inhibitor 10
Biological Activity：Chitin synthase inhibitor 10 is a chitin synthase (CHS) inhibitor. Chitin synthase inhibitor 10 shows excellent CHS inhibitory activity with an IC50 value of 0.11 mM. Chitin synthase inhibitor 10 also is an antifungal agent and has significantly antifungal activity against drug-resistant fungal variants, such as C. albicans and C. neoformans. Chitin synthase inhibitor 10 can be used for the research of invasive fungal infections (IFIs).
Research Area：Cancer|Infection
Targets：Fungal
Related Small Molecules:Antifungal agent 20;Debneyol;Haloprogin;Staurosporine;Ciclopirox-d11;Ciclopirox olamine;Clotrimazole-d5;(R)-Camptothecin-d5;Ticlatone;Aminothiazole;Magnesium silicate;α-Terpinene;Hydroxyphenyllactic acid;Iprobenfos;Chlorphenesin;Moniliformin sodium salt;HLF1-11;β-Amyrin acetate;Bifonazole;Aszonapyrone A;Oenothein B;Pyrimorph;(+)-Magnoflorine iodide;Antifungal agent 39
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Structurally and synthetically diverse biologically active compounds；
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