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ATR-IN-14

CAS No. : 2765785-88-2

Biological Activity：ATR-IN-14 (compound 1) is a potent ATR kinase inhibitor. ATR-IN-14 inhibits ATR signaling pathways downstream CHKI protein phosphorylation, with inhibition of 98.03% at 25 nM. ATR-IN-14 shows good anticancer activity in LoVo cells, with an IC₅₀ of 64 nM.

Research Area：Cancer

Targets：ATM/ATR

Related Small Molecules:ATR-IN-16;ATR-IN-4;CGK733;Ceralasertib;KU 59403;ATM Inhibitor-1;ATR-IN-5;ATR inhibitor 1;VE-821;KU-55933;Garcinone C;SKLB-197;ATR-IN-18;AZD0156;CP-466722;Mirin;ATR-IN-13;Antitumor agent-28;ATR-IN-11;ATR-IN-8;AZ31;ATR-IN-12;ATR-IN-20;ATM Inhibitor-2;Elimusertib;Ro 90-7501;Gartisertib;ATR-IN-7;ATR-IN-17;KU-60019

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