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CAS No. : 1246207-65-7

Biological Activity:INCB38579 is an orally active, highly brain penetrable, and selective histamine H4 receptor (HH4R) antagonist (hH4R IC50=4.8 nM, mH4R IC50=42 nM, rH4R IC50=32 nM). INCB38579 shows anti-inflammatory pain and anti-pruritic activities.

Research Area:Infection

Targets:Histamine Receptor

Related Screening Libraries:Bioactive Compound Library Plus;Anti-Infection Compound Library;GPCR/G Protein Compound Library;Immunology/Inflammation Compound Library;Neuronal Signaling Compound Library;CNS-Penetrant Compound Library;Orally Active Compound Library;Neurotransmitter Receptor Compound Library;Anti-Parkinson’s Disease Compound Library;Neurodegenerative Disease-related Compound Library;Anti-Obesity Compound Library;Coagulation and Anti-coagulation Compound Library;

Related Small Molecules:Tripelennamine;Brompheniramine-d6 maleate;Samelisant;Chlorphenoxamine;H3 receptor-MO-1;Diphenhydramine;ABT-239;Ketotifen fumarate;Ranitidine;Cetirizine;Diphenylpyraline hydrochloride;Loratadine-d5;Phenyltoloxamine;Ritanserin;BMY-25271;FRG8701;Mecamylamine hydrochloride;Cimetidine sulfoxide;Brompheniramine maleate;Tecastemizole;Famotidine-13C,d3;Bromazine-d6 hydrochloride

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