Meclofenoxate hydrochloride

CAS No. : 3685-84-5

Biological Activity：Meclofenoxate hydrochloride, an ester of dimethylethanolamine (DMAE) and 4-chlorophenoxyacetic acid (pCPA), has been shown to improve memory, have a mentally stimulating effect, and improve general cognition.
IC50 value:
Target: nootropic
Meclofenoxate, administered in a dose of 50 mg/kg twice daily for 7 days using the maze-training method, increased the number of responses to the conditioned stimulus, when retention tests were made 24 hours and 7 days after training, whereas citicholine, applied in the same way in a dose of 10 mg/kg, shortened the latency of the responses with reinforcement during the training and increased the number of correct responses to the conditioned stimulus in retention tests 7 days after the training [1]. Meclofenoxate appears to increase the consolidation of new information into long-term memory, but does not affect other aspects of remembering [2].

Research Area：Neurological Disease

Targets：nAChR|iGluR

Related Screening Libraries:Drug Repurposing Compound Library Plus;FDA-Approved Drug Library Plus;FDA-Approved Drug Library Mini;Bioactive Compound Library Plus;Membrane Transporter/Ion Channel Compound Library;Neuronal Signaling Compound Library;FDA-Approved Drug Library;Drug Repurposing Compound Library;NMPA-Approved Drug Library;Neurotransmitter Receptor Compound Library;FDA Approved & Pharmacopeial Drug Library;Anti-Parkinson’s Disease Compound Library;Neurodegenerative Disease-related Compound Library;Antidepressant Compound Library;Human Metabolite Library;

Related Small Molecules:Spinosad;CIQ;Quinolinic acid-d3;Pyrantel;1-Aminocyclobutanecarboxylic acid;Glycine-1-13C,15N;NS 9283;Myosmine-d4;ZL006;PYD-106;Benzethonium chloride;NMDA-IN-2;Dihydro-β-erythroidine;JAMI1001A;(S)-Willardiine;A-867744;Catestatin;Fanapanel;(S)-AMPA;Asoxime dichloride;α7 nAchR-JAK2-STAT3 agonist 1;AR-R17779 hydrochloride;Mecamylamine hydrochloride;L-Glutamic acid-15N,d5;PDZ1 Domain inhibitor peptide TFA;Ifenprodil tartrate;Rislenemdaz

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