Tag: Antagonist|Inducer

For research use only. We do not sell to patients. Macitentan-d4 CAS No. : 1258428-05-5 Biological Activity：Macitentan D4 (ACT-064992 D4) is a deuterium labeled Sulfamethoxazole. Macitentan is an orally active, non-peptide dual ETA and ETB (endothelin) receptor antagonist. Macitentan has the potential for idiopathic pulmonary fibrosis (IPF) and pulmonary arterial hypertension (PAH). Research Area：Cardiovascular Disease […]

For research use only. We do not sell to patients. Enzalutamide CAS No. : 915087-33-1 Biological Activity：Enzalutamide (MDV3100) is an androgen receptor (AR) antagonist with an IC50 of 36 nM in LNCaP prostate cells. Enzalutamide is an autophagy activator[2]. Research Area：Cancer Targets：Androgen Receptor|Autophagy Related Screening Libraries:Drug Repurposing Compound Library Plus;FDA-Approved Drug Library Plus;FDA-Approved Drug Library […]

For research use only. We do not sell to patients. Rupatadine CAS No. : 158876-82-5 Biological Activity：Rupatadine (UR-12592) is a potent, orally active and long-lasting dual PAF/H1 antagonist, with Kis of 0.55 μM and 0.1 μM, respectively. Rupatadine can be used for the research of allergic rhinitis and urticaria[2][3]. Research Area：Inflammation/Immunology Targets：Autophagy|Histamine Receptor Related Small […]

For research use only. We do not sell to patients. SCH79797 CAS No. : 245520-69-8 Biological Activity：SCH79797 is a highly potent, selective nonpeptide protease activated receptor 1 (PAR1) antagonist. SCH79797 inhibits binding of a high-affinity thrombin receptor-activating peptide to PAR1 with an IC50 of 70 nM and a Ki of 35 nM. SCH79797 inhibits thrombin-induced […]