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Plitidepsin

CAS No. : 137219-37-5

Biological Activity：Plitidepsin (Aplidine) is a potent anti-cancer agent by targeting eEF1A2 ( K_D=80 nM). Plitidepsin possesses antiviral activity and is against SARS-CoV-2 with an IC₉₀ of 0.88 nM. Plitidepsin is usually used for multiple myeloma and advanced cancer research, and has the potential for COVID-19 research^[2].

Research Area：Cancer|Infection

Targets：DNA/RNA Synthesis|SARS-CoV

Related Screening Libraries:Natural Product Library Plus;Drug Repurposing Compound Library Plus;FDA-Approved Drug Library Plus;Bioactive Compound Library Plus;Macrocyclic Compound Library;Peptide Library;Cyclic Peptide Library;

Related Small Molecules:Ametantrone;ddCTP trisodium;7-TFA-ap-7-Deaza-dA;P1788;SARS-CoV-2-IN-33;Thymidine-13C5,15N;NSC 617145;GRL-0496;116-9e;DNA Gyrase-IN-5;DMT-2′-F-Bz-dA;6-Thio-2′-Deoxyguanosine;Antitumor agent-74;Grazoprevir potassium salt;Risdiplam;SARS-CoV-2-IN-19;Molnupiravir;SARS-CoV-2 Mpro-IN-3;TH287 hydrochloride

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