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Win 18446

CAS No. : 1477-57-2

Biological Activity：Win 18446 is an orally active testes-specific enzyme ALDH1a2 inhibitor, with an IC₅₀ of 0.3 μM. Win 18446 reversibly inhibits spermatogenesis in many species and inhibits Retinoic acid (HY-14649) biosynthesis from Retinol (HY-B1342) within the testes^[2].

Research Area：Endocrinology

Targets：Aldehyde Dehydrogenase (ALDH)

Related Screening Libraries:Bioactive Compound Library Plus;Metabolism/Protease Compound Library;Endocrinology Compound Library;Orally Active Compound Library;Glutamine Metabolism Compound Library;Anti-Cancer Metabolism Compound Library; Human Metabolite Library;Cancer Stem Cells Compound Library;

Related Small Molecules:Alda-1;ALDH3A1-IN-2;NCT-501 hydrochloride;ALDH1A3-IN-2;CM10;EN40;Prunetin;ALDH1A1-IN-3;Taraxerone;RV01;KS100;CM037;IGUANA-1 free base;4-Diethylaminobenzaldehyde;CVT-10216;KS106;α-NETA;ALDH1A2-IN-1;CM121;ALDH1A3-IN-1;3-Hydroxybenzaldehyde;ALDH3A1-IN-1;NCT-505;4-Hydroxynonenal-d3;NCT-506;ALDH1A3-IN-3;Dyclonine hydrochloride

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