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SC75741
CAS No. : 913822-46-5
Biological Activity：SC75741 is a broad and efficient NF-κB inhibitor with an IC50 of 200 nM for p65. SC75741 blocks influenza viruses (IV) replication. SC75741 impairs DNA binding of the NF-κB subunit p65, resulting in reduced expression of cytokines, chemokines, and pro-apoptotic factors. SC75741 subsequently inhibits caspase activation and blocks caspase-mediated nuclear export of viral ribonucleoproteins[2].
Research Area：Infection|Cancer
Targets：Influenza Virus|NF-κB
Related Screening Libraries:Bioactive Compound Library Plus;Anti-Infection Compound Library;Immunology/Inflammation Compound Library;NF-κB Signaling Compound Library;Stem Cell Signaling Compound Library;Anti-Cancer Compound Library;Antiviral Compound Library;Anti-Aging Compound Library;Antioxidant Compound Library;Differentiation Inducing Compound Library;Oxygen Sensing Compound Library;Pyroptosis Compound Library;Anti-Breast Cancer Compound Library;Anti-Pancreatic Cancer Compound Library;Anti-Blood Cancer Compound Library;Anti-Cancer Metabolism Compound Library;Anti-Obesity Compound Library;Transcription Factor-Targeted Library;Anti-Liver Cancer Compound Library ;Antidepressant Compound Library;Anti-Prostate Cancer Compound Library;Cancer Stem Cells Compound Library;
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