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Gefitinib-based PROTAC 3
CAS No. : 2230821-27-7
Biological Activity：Gefitinib-based PROTAC 3, conjugating an EGFR binding element to a von Hippel-Lindau ligand via a linker, induces EGFR degradation with DC50s of 11.7 nM and 22.3 nM in HCC827(exon 19 del) and H3255 (L858R mutantion) cells, respectively.
Research Area：Cancer
Targets：EGFR|PROTACs
Related Screening Libraries:Bioactive Compound Library Plus;
Related Small Molecules:PROTAC Sirt2 Degrader-1;DB0614;NSC81111;pp60 (v-SRC) Autophosphorylation Site, Phosphorylated;BMS-690514;PROTAC VEGFR-2 degrader-2;dTAGV-1-NEG;CCT367766 formic;Osimertinib-13C,d3;EGFR-IN-5;FGFR2-IN-3;HDAC6 degrader-1;PROTAC Axl Degrader 2;PhosTAC7;MS98;Genistein;Epertinib hydrochloride;JPS014;PROTAC PARP1 degrader;UNC-CA359;MD-224;FKBP12 PROTAC dTAG-7;Osimertinib mesylate;AV-412 free base;Nelipepimut-S;Falnidamol;SJ10542
Trending products：Recombinant Proteins | Bioactive Screening Libraries | Natural Products | Fluorescent Dye | PROTAC | Isotope-Labeled Compounds | Oligonucleotides
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