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Nimbolide
CAS No. : 25990-37-8
Biological Activity：Nimbolide is a triterpene derived from the leaves and flowers of neem (Azadirachta indica). Nimbolide induces apoptosis through inactivation of NF-κB. Nimbolide inhibits CDK4/CDK6 kinase activity. Nimbolide suppresses the NF-κB, Wnt, PI3K-Akt, MAPK and JAK-STAT signaling pathways.
Research Area：Cancer
Targets：NF-κB|CDK|Apoptosis
Related Screening Libraries:Covalent Screening Library Plus;Natural Product Library Plus;Bioactive Compound Library Plus;Apoptosis Compound Library;Cell Cycle/DNA Damage Compound Library;Immunology/Inflammation Compound Library;Kinase Inhibitor Library;NF-κB Signaling Compound Library;Stem Cell Signaling Compound Library;Natural Product Library;Anti-Cancer Compound Library;Anti-Aging Compound Library;Covalent Screening Library;Antioxidant Compound Library;Differentiation Inducing Compound Library;Oxygen Sensing Compound Library;Terpenoids Library;Pyroptosis Compound Library;Anti-Breast Cancer Compound Library;Anti-Pancreatic Cancer Compound Library;Anti-Blood Cancer Compound Library;Anti-Cancer Metabolism Compound Library;Anti-Obesity Compound Library;Transcription Factor-Targeted Library;Anti-Liver Cancer Compound Library ;Anti-Cancer Natural Product Library;Antidepressant Compound Library;Plant-Sourced Natural Product Library;Anti-Prostate Cancer Compound Library;Cancer Stem Cells Compound Library;
Related Small Molecules:Physalin A;Bomedemstat ditosylate;Akt/NF-κB/JNK-IN-1;DB0614;Enpp/Carbonic anhydrase-IN-1;GK563;Calpeptin;Lobetyolin;Icariside F2;BJE6-106;Dinaciclib;Ecteinascidin 770;MDM2-p53-IN-15;IKKγ NBD Inhibitory Peptide TFA;AT9283;Staurosporine;SNS-032;C188-9;ZLDI-8;Topoisomerase I/II inhibitor 3;CC-671;Xevinapant;Mangiferin;Cambinol;Antioxidant agent-5
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