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Pyrimethamine
CAS No. : 58-14-0
Biological Activity：Pyrimethamine (Pirimecidan) is a potent, orally active dihydrofolate reductase (DHFR) inhibitor. Pyrimethamine is an antimalarial agent. Pyrimethamine affects the nucleoprotein metabolism of malarial parasites by interference in the folic–folinic acid systems and affects cell division by inhibiting the conversion of dihydrofolate to tetrahydrofolate[2].
Research Area：Infection
Targets：Parasite|Antifolate
Related Screening Libraries:Drug Repurposing Compound Library Plus;FDA-Approved Drug Library Plus;FDA-Approved Drug Library Mini;Bioactive Compound Library Plus;Anti-Infection Compound Library;Cell Cycle/DNA Damage Compound Library;FDA-Approved Drug Library;Antiviral Compound Library;CNS-Penetrant Compound Library;Anti-Aging Compound Library;Drug Repurposing Compound Library;NMPA-Approved Drug Library;Orally Active Compound Library;FDA Approved & Pharmacopeial Drug Library;Drug-Induced Liver Injury (DILI) Compound Library;Antiparasitic Compound library;Anti-Cancer Metabolism Compound Library;Rare Diseases Drug Library;Children’s Drug Library;Human Metabolite Library;
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