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YUKA1

CAS No. : 708991-09-7

Biological Activity：YUKA1 is a potent and cell permeable Lysine demethylase 5A (KDM5A) inhibitor, with an IC₅₀ of 2.66 μM, less active on KDM5C (IC₅₀, 7.12 μM), and is inactive on KDM5B, KDM6A or KDM6B. YUKA1 increases H3K4me3 levels in human cells with anti-cancer activity.

Research Area：Cancer

Targets：Histone Demethylase

Related Small Molecules:Bomedemstat ditosylate;LSD1/ER-IN-1;PBIT;JQKD82;KDOAM-25 citrate;GSK-J1 lithium salt;S2116;LSD1-IN-16;TAK-418;NCGC00247743;DS17701585;KDM2B-IN-3;S2101;LSD1/2-IN-3;KDM5-IN-1;GSK467;S2157;PFI-90;FY-56;Eicosapentaenoic Acid;LSD1-IN-20;KDM5A-IN-1;Bizine;Procaine-d4 hydrochloride

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