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Patritumab

CAS No. : 1262787-83-6

Biological Activity：Patritumab (Human Anti-ERBB3 Recombinant Antibody) is a neutralizing monoclonal antibody to ERBB3. Patritumab shows a synergy with Cetuximab (HY-P9905), potently inhibits the phosphorylation of EGFR, HER2, HER3, ERK, and AKT. Patritumab also induces cell apoptosis and suppresses the growth of pancreatic, non-small cell lung cancer, and colorectal cancer xenograft tumors.

Research Area：Cancer

Targets：EGFR|Akt|PARP|Survivin|ERK

Related Small Molecules:Akt/NF-κB/JNK-IN-1;NSC81111;pp60 (v-SRC) Autophosphorylation Site, Phosphorylated;BMS-690514;Cyclovirobuxine D;Rucaparib monocamsylate;AZD-2461;Senaparib;Osimertinib-13C,d3;Dehydrocorydaline;AKTide-2T;EGFR-IN-5;FGFR2-IN-3;Rucaparib hydrochloride;Sennidin A;MS98;Niraparib tosylate;Genistein;Epertinib hydrochloride;PP2A Cancerous-IN-1;1,3-Dicaffeoylquinic acid;Sepantronium bromide;Corynoxeine;G007-LK;PROTAC PARP1 degrader;UNC-CA359;Artemisiane E;Osimertinib mesylate

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