GPR84 antagonist 2

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GPR84 antagonist 2

CAS No. : 2244269-74-5

Biological Activity:GPR84 antagonist 2 (compound 33) is a potent, selective, and orally active GPR84 antagonist (IC50=8.95 nM). GPR84 antagonist 2 shows improved potency in the calcium mobilization assay and the ability to inhibit the chemotaxis of neutrophils and macrophages upon GPR84 activation. GPR84 antagonist 2 has the potential for the research of ulcerative colitis.

Research Area:Inflammation/Immunology

Targets:GPR84

Related Small Molecules:GPR84 antagonist 3;GLPG1205;6-OAU;GPR84 antagonist 8;GPR84 antagonist 1;Fezagepras

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