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PLX-4720-d7
CAS No. : 1304096-50-1
Biological Activity：PLX-4720-d7 is the deuterium labeled PLX-4720. PLX-4720 is a potent and selective inhibitor of B-RafV600E with an IC50 of 13 nM in a cell-free assay, equally potent to c-Raf-1(Y340D and Y341D mutations), and 10-fold selectivity for B-RafV600E than wild-type B-Raf[2].
Research Area：Cancer
Targets：Raf
Related Small Molecules:Avutometinib;AZ 628;Everafenib;L-779450;Raf inhibitor 1;PLX-4720;RRD-251;B-Raf IN 8;TAK-632;Encorafenib;RAF mutant-IN-1;AD80;CCT241161;PLX7904;RAF-IN-1;EGFR/BRAFV600E-IN-1;MCP110;GDC-0879;B-Raf IN 1;R18;Rineterkib
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