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Vevorisertib trihydrochloride
CAS No. : 1416775-08-0
Biological Activity：Vevorisertib (ARQ 751) trihydrochloride is a selective, allosteric, pan-AKT and AKT1-E17K mutant inhibitors. Vevorisertib trihydrochloride potently inhibit phosphorylation of AKT. Vevorisertib trihydrochloride has Kd values of 1.2 nM and 8.6 nM for AKT1 and AKT1-E17K, respectively. Vevorisertib trihydrochloride has IC50 values of 0.55, 0.81, and 1.3 nM for AKT1, AKT2, and AKT3, respectively. Vevorisertib trihydrochloride can be used for the research of cancer.
Research Area：Cancer
Targets：Akt
Related Screening Libraries:Clinical Compound Library Plus;Bioactive Compound Library Plus;Kinase Inhibitor Library;PI3K/Akt/mTOR Compound Library;Stem Cell Signaling Compound Library;Anti-Cancer Compound Library;Clinical Compound Library;Autophagy Compound Library;Anti-Aging Compound Library;Differentiation Inducing Compound Library;Oxygen Sensing Compound Library;Glycolysis Compound Library;Cytoskeleton Compound Library;Orally Active Compound Library;Glutamine Metabolism Compound Library;Anti-Breast Cancer Compound Library;Anti-Lung Cancer Compound Library;Anti-Pancreatic Cancer Compound Library;Anti-Blood Cancer Compound Library;Anti-Cancer Metabolism Compound Library;Anti-Obesity Compound Library;Angiogenesis-Related Compound Library;Glucose Metabolism Compound Library;Anti-Liver Cancer Compound Library ;Anti-Colorectal Cancer Compound Library ;Anti-Prostate Cancer Compound Library;Anti-Pulmonary Fibrosis Compound Library;Cancer Stem Cells Compound Library;
Related Small Molecules:Akt/NF-κB/JNK-IN-1;Cyclovirobuxine D;AKTide-2T;Sennidin A;MS98;PP2A Cancerous-IN-1;1,3-Dicaffeoylquinic acid;Artemisiane E;Artemisinin-d3;AS1949490;PI3K-IN-29;TD52 dihydrochloride;LM22B-10;AT13148;Pachymic acid;Glaucocalyxin A;PI3K/AKT-IN-2;INY-03-041;N-Oleoyl glycine;Triciribine;CCT128930;Chromeceptin;YS-49;AKT-IN-12;Licoricidin;A-443654;PI3K/AKT-IN-1;AKT-IN-9;GSK2110183 analog 1;MS5033
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