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FIIN-1
CAS No. : 1256152-35-8
Biological Activity:FIIN-1 is a potent, irreversible, selective FGFR inhibitor. FIIN-1 binds to FGFR1/2/3/4 and Flt1/4 with Kds of 2.8/6.9/5.4/120 nM and 32/120 nM respectively. The biochemical IC50s of FIIN-1 are 9.2, 6.2, 11.9, and 189 nM against FGFR1/2/3/4, respectively.
Research Area:Cancer
Targets:FGFR
Related Small Molecules:Ferulic acid-13C3;FGFR-IN-7;PP58;FGFR3-IN-1;ENMD-2076 Tartrate;R1530;FGFR3-IN-3;Tyrosine kinase-IN-1;Heparan Sulfate;Futibatinib;SU4984;Roblitinib;PD173074;PF 477736;FGFR4-IN-8;Lucitanib;Masitinib;Zoligratinib;FGFR4-IN-4;BLU9931;SM1-71;VSPPLTLGQLLS TFA;TG 100801;FGFR1 inhibitor-6
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