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ML-211

CAS No. : 2205032-89-7

Biological Activity：ML-211 is a carbamate-based dual inhibitor of acyl-protein thioesterase 1 (APT1)/lysophospholipase 1 (LYPLA1) (IC₅₀=17 nM) and LYPLA2 (IC₅₀=30 nM). ML-211 also inhibits theserine hydrolase ABHD11 with an IC₅₀ value of 10 nM but is ≥ 50-fold selective for LYPLA in a panel of 20 additional serine hydrolases.

Targets：MAGL|Phospholipase

Related Small Molecules:GK563;DPTIP;Cambinol;Neomycin sulfate;ONO-RS-082;ARN19874;LEI-401;ST271;Melittin TFA;(S)-Bromoenol lactone;GK187;D-Erythro-dihydrosphingosine-d7;FKGK11;PACOCF3;DL-erythro-Dihydrosphingosine;1-Naphthaleneacetic acid potassium salt;C12 NBD Sphingomyelin;ML-298;MAGL-IN-6;PF-06795071;JZL195;sPLA2-X Inhibitor 31;N-Arachidonyl maleimide;Tanshinone I;ML-​226;(R)-Bromoenol lactone;JW 642

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