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RHC 80267
CAS No. : 83654-05-1
Biological Activity：RHC 80267 (U-57908) is a potent and selective inhibitor of diacylglycerol lipase (DAGL) (with IC50 of 4 μM in canine platelets). RHC-80267 inhibits cholinesterase activity with an IC50 of 4 μM, thereby enhancing the relaxation evoked by acetylcholine. RHC 80267 also inhibits COX and the hydrolysis of phosphatidylcholine (PC)[2][3][4].
Research Area：Metabolic Disease|Neurological Disease
Targets：mAChR|Acyltransferase|Phospholipase|COX
Related Screening Libraries:Bioactive Compound Library Plus;
Related Small Molecules:VU0357017 hydrochloride;Akt/NF-κB/JNK-IN-1;GK563;COX-2/5-LOX-IN-3;DPTIP;RP-64477;Enniatin A;TBPB;Imidafenacin;Cambinol;Sabcomeline;Neomycin sulfate;ONO-RS-082;Ampyrone;MK-6884;COX-2-IN-24;Brompheniramine-d6 maleate;Zaltoprofen-d7;IWP-12;ARN19874;LEI-401;ST271;α-Vitamin E-d6;1-Hydroxy-ibuprofen;Asaraldehyde;(-)-Epicatechin
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