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CAY10566

CAS No. : 944808-88-2

Biological Activity：CAY10566 is a potent, orally bioavailable and selective stearoyl-CoA desaturase1 (SCD1) inhibitor with IC₅₀s of 4.5 and 26 nM in mouse and human enzymatic assays, respectively.
CAY10566 also shows excellent cellular activity in blocking the conversion of saturated long-chain fatty acid-CoAs (LCFA-CoAs) to monounsaturated LCFA-CoAs in HepG2 cells (IC₅₀=7.9 nM or 6.8 nM)^[2].

Research Area：Cancer

Targets：Stearoyl-CoA Desaturase (SCD)

Related Screening Libraries:Bioactive Compound Library Plus;Metabolism/Protease Compound Library;Anti-Cancer Compound Library;Orally Active Compound Library;Anti-Cancer Metabolism Compound Library;Anti-Obesity Compound Library;Lipid Metabolism Compound Library ;

Related Small Molecules:SCD1 inhibitor-3;Icomidocholic acid;T-3764518;Sterculic acid;SCD1 inhibitor-1;XEN723;MF-438;MK-8245 Trifluoroacetate;CVT-11127;Elemicin;CVT-12012;SCD1 inhibitor-4;PluriSIn 1;A939572;YTX-465;SCD1-IN-1;GSK1940029

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