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ZL0580
CAS No. : 2377151-10-3
Biological Activity:ZL0580, a structurally close analog of ZL0590, induces epigenetic suppression of HIV via selectively binding to BD1 domain of BRD4. ZL0580 induces HIV suppression by inhibiting Tat transactivation and transcription elongation as well as by inducing repressive chromatin structure at the HIV promoter[2][3].
Research Area:Infection|Inflammation/Immunology
Targets:Epigenetic Reader Domain|HIV
Related Screening Libraries:Covalent Screening Library Plus;Bioactive Compound Library Plus;Anti-Infection Compound Library;Epigenetics Compound Library;Immunology/Inflammation Compound Library;Histone Modification Research Compound Library;Antiviral Compound Library;Covalent Screening Library;Anti-Blood Cancer Compound Library;
Related Small Molecules:RVX-297;BRD4 Inhibitor-19;HIV-1 TAT (48-60);Seletracetam lithium;HIV-IN-2;UNC6349 (Ket2);Curcumin;Triptonine B;GSK6853;GSK4028;FC131;Peritassine A;SR-0813;Flavopiridol;Inobrodib;TAT (48-57);FGI-106 tetrahydrochloride;(Z)-9-Propenyladenine;Apabetalone;OF-1;I-CBP112;Decanoyl-RVKR-CMK TFA;ONX-0914 TFA
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