Product Name :
COMT Recombinant Rabbit Monoclonal Antibody [JG39-48]
Predicted band size :
Observed band size :
Synonyms:
Catechol O methyltransferase antibody Catechol O-methyltransferase antibody COMT antibody COMT_HUMAN antibody EC 2.1.1.6 antibody
Function :
Catechol-O-methyltransferase (COMT) plays a crucial role in the regulation of central dopaminergic systems by catalyzing the inactivation of catechol-amines. It is widely distributed in most tissues in soluble and membrane-bound forms. COMT-mediated methylation metabolism of catecholamine neurotransmitters is a first-line detoxification pathway. A Val158Met polymorphism of the COMT gene affects activity of the enzyme and influences performance and efficiency of the prefrontal cortex of the brain. Sequential conversion of estradiol to methoxyestradiol by COMT, contributes to the antimitogenic effects of estradiol on vascular smooth muscle cell growth via estrogen receptor-independent mechanisms.
Antibody Type:
Recombinant Rabbit monoclonal Antibody
Immunogen :
Recombinant protein within COMT aa 11-107 / 271.{{Pyrazinamide} site|{Pyrazinamide} Anti-infection|{Pyrazinamide} Technical Information|{Pyrazinamide} Description|{Pyrazinamide} supplier|{Pyrazinamide} Cancer}
Species reactivity:
Human, Mouse, Rat
Verify application:
WB, IHC-P
Coupling :
unconjugated
Clone number:
JG39-48
RRID:
AB_3070882
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing.{{Lisinopril dihydrate} web|{Lisinopril dihydrate} Metabolic Enzyme/Protease|{Lisinopril dihydrate} Technical Information|{Lisinopril dihydrate} Description|{Lisinopril dihydrate} supplier|{Lisinopril dihydrate} Epigenetic Reader Domain} Aliquot store at -20℃.PMID:24211511 Avoid repeated freeze / thaw cycles.
Storage buffer solution:
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
24 kDa
Positive control :
MCF-7, rat testis tissue lysate, mouse testis tissue.