Product Name :
Balovaptan
Description:
Balovaptan (RG7314) is a highly potent and selective brain-penetrant vasopressin 1a (hV1a) receptor antagonist, with Kis of 1 and 39 nM for human (hV1a) and mouse (mV1a) receptors, and is used for the research of autism.
CAS:
1228088-30-9
Molecular Weight:
409.91
Formula:
C22H24ClN5O
Chemical Name:
12-chloro-8-methyl-3-[4-(pyridin-2-yloxy)cyclohexyl]-2,4,5,8-tetraazatricyclo[8.4.0.0²,⁶]tetradeca-1(14),3,5,10,12-pentaene
Smiles :
CN1CC2=CC(Cl)=CC=C2N2C(=NN=C2C1)C1CCC(CC1)OC1=CC=CC=N1
InChiKey:
GMPZPHGHNDMRKL-UHFFFAOYSA-N
InChi :
InChI=1S/C22H24ClN5O/c1-27-13-16-12-17(23)7-10-19(16)28-20(14-27)25-26-22(28)15-5-8-18(9-6-15)29-21-4-2-3-11-24-21/h2-4,7,10-12,15,18H,5-6,8-9,13-14H2,1H3
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Balovaptan (RG7314) is a highly potent and selective brain-penetrant vasopressin 1a (hV1a) receptor antagonist, with Kis of 1 and 39 nM for human (hV1a) and mouse (mV1a) receptors, and is used for the research of autism.|Product information|CAS Number: 1228088-30-9|Molecular Weight: 409.91|Formula: C22H24ClN5O|Chemical Name: 12-chloro-8-methyl-3-[4-(pyridin-2-yloxy)cyclohexyl]-2,4,5,8-tetraazatricyclo[8.4.0.0²,⁶]tetradeca-1(14),3,5,10,12-pentaene|Smiles: CN1CC2=CC(Cl)=CC=C2N2C(=NN=C2C1)C1CCC(CC1)OC1=CC=CC=N1|InChiKey: GMPZPHGHNDMRKL-UHFFFAOYSA-N|InChi: InChI=1S/C22H24ClN5O/c1-27-13-16-12-17(23)7-10-19(16)28-20(14-27)25-26-22(28)15-5-8-18(9-6-15)29-21-4-2-3-11-24-21/h2-4,7,10-12,15,18H,5-6,8-9,13-14H2,1H3|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : 62.5 mg/mL (152.47 mM; Need ultrasonic).|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Dotriacontane} MedChemExpress|{Dotriacontane} Technical Information|{Dotriacontane} Data Sheet|{Dotriacontane} supplier|{Dotriacontane} Autophagy} |Shelf Life: ≥12 months if stored properly.{{Ivacaftor} MedChemExpress|{Ivacaftor} Autophagy|{Ivacaftor} Purity & Documentation|{Ivacaftor} Description|{Ivacaftor} manufacturer|{Ivacaftor} Epigenetics} |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:24507727 |Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|Balovaptan (RG7314) is a highly potent and selective brain-penetrant vasopressin 1a (hV1a) receptor antagonist, with Kis of 1 and 39 nM for hV1a and mhV1a, and is used for the research of autism. Balovaptan shows >30000-fold selectivity for hV1a over hV2 receptors, 9891-fold selectivity over hOTR (human oxytocin receptor).|Products are for research use only. Not for human use.|