ALK2-IN-1

Product Name :
ALK2-IN-1

Description:
ALK2-IN-1 is a activin receptor-like kinase-2 (ALK2) inhibitor extracted from patent WO2017181117A1, Compound 876, has an IC50 of <10 nM

CAS:
2141955-96-4

Molecular Weight:
562.70

Formula:
C31H42N6O4

Chemical Name:
1-Piperazinecarboxylic acid, 4-[6-[5-[4-ethoxy-1-(1-methylethyl)-4-piperidinyl]-2-pyridinyl]pyrrolo[1,2-b]pyridazin-4-yl]-, (3R)-tetrahydro-3-furanyl ester

Smiles :
CC(C)N1CCC(CC1)(OCC)C1=CN=C(C=C1)C1C=C2C(=CC=NN2C=1)N1CCN(CC1)C(=O)O[C@H]1COCC1

InChiKey:
SWVYYNLRVIYURK-AREMUKBSSA-N

InChi :
InChI=1S/C31H42N6O4/c1-4-40-31(9-12-34(13-10-31)23(2)3)25-5-6-27(32-20-25)24-19-29-28(7-11-33-37(29)21-24)35-14-16-36(17-15-35)30(38)41-26-8-18-39-22-26/h5-7,11,19-21,23,26H,4,8-10,12-18,22H2,1-3H3/t26-/m1/s1

Purity:
≥98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life:
≥12 months if stored properly.

Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.{{Phenformin} web|{Phenformin} Epigenetics|{Phenformin} Activator|{Phenformin} Protocol|{Phenformin} In Vitro|{Phenformin} manufacturer}

Additional information:
ALK2-IN-1 is a activin receptor-like kinase-2 (ALK2) inhibitor extracted from patent WO2017181117A1, Compound 876, has an IC50 of Product information|CAS Number: 2141955-96-4|Molecular Weight: 562.{{Tefibazumab} MedChemExpress|{Tefibazumab} Technical Information|{Tefibazumab} Formula|{Tefibazumab} custom synthesis|{Tefibazumab} Autophagy} 70|Formula: C31H42N6O4|Synonym:|BLU-782|Chemical Name: 1-Piperazinecarboxylic acid, 4-[6-[5-[4-ethoxy-1-(1-methylethyl)-4-piperidinyl]-2-pyridinyl]pyrrolo[1,2-b]pyridazin-4-yl]-, (3R)-tetrahydro-3-furanyl ester|Smiles: CC(C)N1CCC(CC1)(OCC)C1=CN=C(C=C1)C1C=C2C(=CC=NN2C=1)N1CCN(CC1)C(=O)O[C@H]1COCC1|InChiKey: SWVYYNLRVIYURK-AREMUKBSSA-N|InChi: InChI=1S/C31H42N6O4/c1-4-40-31(9-12-34(13-10-31)23(2)3)25-5-6-27(32-20-25)24-19-29-28(7-11-33-37(29)21-24)35-14-16-36(17-15-35)30(38)41-26-8-18-39-22-26/h5-7,11,19-21,23,26H,4,8-10,12-18,22H2,1-3H3/t26-/m1/s1|Technical Data|Appearance: Solid Power.PMID:24190482 |Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: Soluble in DMSO|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined.|HS Tariff Code: 382200|References:|Natasja Brooijmans, et al. Inhibitors of activin receptor-like kinase. WO2017181117A1.Products are for research use only. Not for human use.|

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