Product Name :
CLASP1 Recombinant Rabbit Monoclonal Antibody [JE43-19]
Predicted band size :
169 kDa
Observed band size :
150 kDa
Synonyms:
1700030C23Rik antibody 5730583A19Rik antibody B130045P17Rik antibody CLAP1_HUMAN antibody clasp1 antibody CLIP associating protein 1 antibody CLIP associating protein CLASP1 antibody CLIP-associating protein 1 antibody Cytoplasmic linker associated protein 1 antibody Cytoplasmic linker-associated protein 1 antibody 展开
Function :
Microtubule plus-end tracking protein that promotes the stabilization of dynamic microtubules. Involved in the nucleation of noncentrosomal microtubules originating from the trans-Golgi network (TGN).{{MT1} web|{MT1} Epigenetic Reader Domain|{MT1} Protocol|{MT1} Formula|{MT1} custom synthesis|{MT1} Autophagy} Required for the polarization of the cytoplasmic microtubule arrays in migrating cells towards the leading edge of the cell.{{Staphylokinase} MedChemExpress|{Staphylokinase} Purity & Documentation|{Staphylokinase} In stock|{Staphylokinase} custom synthesis|{Staphylokinase} Autophagy} May act at the cell cortex to enhance the frequency of rescue of depolymerizing microtubules by attaching their plus-ends to cortical platforms composed of ERC1 and PHLDB2. This cortical microtubule stabilizing activity is regulated at least in part by phosphatidylinositol 3-kinase signaling. Also performs a similar stabilizing function at the kinetochore which is essential for the bipolar alignment of chromosomes on the mitotic spindle.
Antibody Type:
Recombinant Rabbit monoclonal Antibody
Immunogen :
Synthetic peptide within Human CLASP1 aa 1-50 / 1,538.
Species reactivity:
Human, Mouse, Rat
Verify application:
WB, IF-Cell, IF-Tissue, IHC-P, FC
Coupling :
unconjugated
Clone number:
JE43-19
RRID:
AB_3070919
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing.PMID:23376608 Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.
Storage buffer solution:
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
Predicted band size: 169 kDa
Positive control :
HepG2 cell lysate, Daudi cell lysate, SH-SY-5Y, SiHa, rat kidney tissue, human stomach tissue, human small intestine tissue, mouse colon tissue.