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CAS No. : 2421135-03-5

Biological Activity:TGFβRI-IN-4 is a highly potent and orally active TGFβ receptor type I (TGFβRI) inhibitor, with IC50s of 44 nM and 42.5 nM for ALK5 and NIH3T3. TGFβRI-IN-4 can suppress tumor growth and tumor weight in tumor xenograft model.

Research Area:Cancer

Targets:TGF-β Receptor

Related Small Molecules:ML347;LDN193189 (GMP);ALK5-IN-6;TGFβ-IN-1;p-nitro-Pifithrin-α;Chromenone 1;OD36;ALK5-IN-32;SB-505124 hydrochloride;K02288;ALK5-IN-28;LY-364947;LY3200882;Itacnosertib;J-1063;Maohuoside A;ALK5-IN-27;Galunisertib;ALK2-IN-4 succinate;SB-431542 (GMP);A 83-01;A 77-01;MU1700;Dorsomorphin;ALK5-IN-34;SM 16;SB 525334

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