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SKF-86002 dihydrochloride

CAS No. : 116339-68-5

Biological Activity：SKF-86002 dihydrochloride is an orally active p38 MAPK inhibitor, with anti-inflammatory, anti-arthritic and analgesic activities. SKF-86002 dihydrochloride inhibits lipopolysaccharide (LPS)-stimulate human monocyte IL-1 and TNF-α production (IC₅₀ = 1 μM). SKF-86002 dihydrochloride inhibits lipoxygenase- and cyclooxygenase-mediated metabolism of arachidonic acid^[2]^[3].

Research Area：Inflammation/Immunology

Targets：p38 MAPK

Related Small Molecules:SB-747651A dihydrochloride;Dehydrocorydaline;Pexmetinib;SB 242235;TA-01;Anti-inflammatory agent 7;MW-150;VX-702;R1487 Hydrochloride;MBP MAPK Substrate;Isoliquiritin apioside;Sesamolin;MAPK13-IN-1;PF-05381941;Semapimod tetrahydrochloride;SD-169;Skatole;BMS-582949 hydrochloride;Gypenoside L;Dilmapimod;Pamapimod;Andrograpanin;MKK7-COV-9;AMG-47a;Kaempferol-3-O-glucorhamnoside;SB 202190 hydrochloride

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