NAPQI

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NAPQI

CAS No. : 50700-49-7

Biological Activity:NAPQI is the toxic metabolite of Acetaminophen (HY-66005). NAPQI is also an inhibitor of enzymes in the vitamin K cycle. NAPQI is rapidly detoxified by glutathione (GSH), but in situations of GSH deficiency, excess NAPQI reacts with cysteine residues in proteins, causing cell death and toxicity in the liver[2].

Research Area:Metabolic Disease

Targets:Endogenous Metabolite

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