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Ifenprodil tartrate

CAS No. : 23210-58-4

Biological Activity：Ifenprodil tartrate is a typical noncompetitive NMDA receptor antagonist. Ifenprodil tartrate exerts high affinity at NR1A/NR2B receptors (IC₅₀=0.34 μM) over 400-fold than at NR1A/NR2A receptors (IC₅₀=146 μM). Ifenprodil tartrate inhibits GIRK (Kir3), reduces inward currents through the basal GIRK activity. Ifenprodil tartrate has the potential to be a cerebral vasodilator^[2].

Research Area：Neurological Disease

Targets：Potassium Channel|iGluR

Related Screening Libraries:Natural Product Library Plus;Drug Repurposing Compound Library Plus;FDA-Approved Drug Library Plus;FDA-Approved Drug Library Mini;Bioactive Compound Library Plus;Membrane Transporter/Ion Channel Compound Library;Neuronal Signaling Compound Library;Natural Product Library;FDA-Approved Drug Library;Drug Repurposing Compound Library;Anti-COVID-19 Compound Library;Neurotransmitter Receptor Compound Library;FDA Approved & Pharmacopeial Drug Library;Anti-Alzheimer’s Disease Compound Library;Neuroprotective Compound Library;Alkaloids Library;Anti-Parkinson’s Disease Compound Library;Neurodegenerative Disease-related Compound Library;Rare Diseases Drug Library;Antidepressant Compound Library;Protein-protein Interaction Inhibitor Library;Plant-Sourced Natural Product Library;Potassium Channel Compound Library;Human Metabolite Library;Anti-Pulmonary Fibrosis Compound Library;

Related Small Molecules:Kv3 modulator 2;CIQ;Quinolinic acid-d3;Brompheniramine-d6 maleate;Pinacidil;1-Aminocyclobutanecarboxylic acid;Glycine-1-13C,15N;AMP-PNP tetralithium;IK1 inhibitor PA-6;VU590;ZL006;Domiphen bromide;PYD-106;Mesoridazine benzenesulfonate;Tetrandrine;NMDA-IN-2;20(S)-Ginsenoside Rg3;(S)-(+)-Modafinic acid-d5;JAMI1001A;(S)-Willardiine;Fanapanel;Ketanserin;(S)-AMPA;PE 22-28;L-Glutamic acid-15N,d5

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