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Harringtonolide
CAS No. : 64761-48-4
Biological Activity：Harringtonolide is a potent RACK1 inhibitor (IC50=39.66 μM in A375 cells). Harringtonolide inhibits the epithelial-mesenchymal transition (EMT) process and cell proliferation by affecting the interaction between FAK and RACK1. Harringtonolide has plant growth inhibitory, antiviral, anti-inflammatory, and antiproliferation activities.
Research Area：Cancer|Inflammation/Immunology
Targets：FAK
Related Small Molecules:FAK-IN-8;BI-4464;FAK inhibitor 5;Masitinib;PF-573228;Chloropyramine hydrochloride;FAK inhibitor 6;FAK-IN-6;Roslin 2 bromide;PROTAC FAK degrader 1;GSK2256098;ALK inhibitor 1;Defactinib;PND-1186;PF-562271 besylate;AMP-945;PF-562271 hydrochloride;FLT3-IN-17;FAK-IN-1;ULK1-IN-2;Y15;YH-306;Petunidin chloride;GSK215;NVP-TAE 226;PDZ1i;ALK inhibitor 2
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