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CAS No. : 1639325-43-1

Biological Activity:Givosiran (ALN-AS1) is a small interfering RNA that targets hepatic aminolevulinate synthase 1 (ALAS1) messenger RNA. Givosiran downregulates ALAS1 mRNA and prevents accumulation of neurotoxic δ-aminolevulinic acid and porphobilinogen levels. Givosiran can be used for the research of acute intermittent porphyria[2].

Research Area:Neurological Disease

Targets:Small Interfering RNA (siRNA)

Related Screening Libraries:Drug Repurposing Compound Library Plus;FDA-Approved Drug Library Plus;Bioactive Compound Library Plus;

Related Small Molecules:SLN124;Cemdisiran;Manusiran;Revusiran;AB-729;Teprasiran;Fazirsiran;Fitusiran;Patisiran sodium;Inclisiran;Tivanisiran;Lumasiran;Elebsiran;Lumasiran sodium;Zerlasiran;Vutrisiran

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