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CAS No. : 1609564-75-1

Biological Activity:DY268 is a farnesoid X receptor (FXR) antagonist (IC50=7.5 nM in a time-resolved FRET assay). It inhibits FXR transactivation in a cell-based assay with an IC50 value of 468 nM.

Research Area:Metabolic Disease


Related Screening Libraries:Bioactive Compound Library Plus;Metabolism/Protease Compound Library;Anti-Obesity Compound Library;Nuclear Receptor Compound Library;

Related Small Molecules:FXR agonist 4;Chenodeoxycholic Acid-d9;EDP-305;Turofexorate isopropyl;Tauro-Obeticholic acid-d5 sodium;Chenodeoxycholic acid-13C;LY2562175;INT-767;BAR502;Glyco-obeticholic acid-d5;NR1H4 activator 1;NDB;BMS-986339;FXR antagonist 1;Guggulsterone;Forskolin;Obeticholic acid-d5;Chenodeoxycholic acid-d5;Nidufexor;Tauro-β-muricholic acid sodium;BMS-986318;Obeticholic acid;T0901317

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