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CAS No. : 1132935-63-7

Biological Activity:Dasabuvir (ABT-333) is a nonnucleoside hepatitis C virus (HCV) polymerase inhibitor. Dasabuvir inhibits RNA-dependent RNA polymerase encoded by the HCV NS5B gene. Dasabuvir inhibits genotype 1a (strain H77) and 1b (strain Con1) replicons, with EC50 values of 7.7 and 1.8 nM, respectively.

Research Area:Infection

Targets:HCV|DNA/RNA Synthesis

Related Screening Libraries:Drug Repurposing Compound Library Plus;FDA-Approved Drug Library Plus;FDA-Approved Drug Library Mini;Bioactive Compound Library Plus;Anti-Infection Compound Library;Cell Cycle/DNA Damage Compound Library;FDA-Approved Drug Library;Antiviral Compound Library;Anti-Aging Compound Library;Drug Repurposing Compound Library;NMPA-Approved Drug Library;FDA Approved & Pharmacopeial Drug Library;Anti-Hepatitis C Virus Compound Library;Drug-Induced Liver Injury (DILI) Compound Library;EMA-Approved Drug Library;Human Metabolite Library;

Related Small Molecules:Ametantrone;HCV-IN-30;ddCTP trisodium;7-TFA-ap-7-Deaza-dA;HCV-IN-38;P1788;Thymidine-13C5,15N;NSC 617145;116-9e;Sennidin A;DNA Gyrase-IN-5;DMT-2′-F-Bz-dA;HCV-IN-31;6-Thio-2′-Deoxyguanosine;Radalbuvir;Antitumor agent-74;Grazoprevir potassium salt;Risdiplam;FGI-106 tetrahydrochloride;TH287 hydrochloride;BMS-986144;Oenothein B

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