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CAS No. : 1421438-81-4

Biological Activity:Crenigacestat (LY3039478) is an orally active Notch and γ-secretase inhibitor, with an IC50 of 1 nM in most of the tumor cell lines tested[2][3][4].

Research Area:Cancer


Related Screening Libraries:Drug Repurposing Compound Library Plus;Clinical Compound Library Plus;Bioactive Compound Library Plus;Neuronal Signaling Compound Library;Stem Cell Signaling Compound Library;Wnt/Hedgehog/Notch Compound Library;Anti-Cancer Compound Library;Clinical Compound Library;Anti-Aging Compound Library;Drug Repurposing Compound Library;Differentiation Inducing Compound Library;Reprogramming Compound Library;Anti-COVID-19 Compound Library;Orally Active Compound Library;Anti-Breast Cancer Compound Library;Anti-Pancreatic Cancer Compound Library;Neurodegenerative Disease-related Compound Library;Angiogenesis-Related Compound Library;Transcription Factor-Targeted Library;Anti-Liver Cancer Compound Library ;Anti-Colorectal Cancer Compound Library ;Cancer Stem Cells Compound Library;

Related Small Molecules:γ-Secretase modulator 4;ELN318463;ZLDI-8;Aβ42-IN-1 free base;Fosciclopirox;FLI-06;JNJ-40418677;gamma-secretase modulator 3;γ-Secretase modulator 11 hydrochloride;γ-Secretase modulator 12;JI051;Aβ42-IN-2;Demcizumab;DAPT (GMP);Notch inhibitor 1;BPN-15606;Tarextumab;Notch 1 TFA;Bruceine D;LY-411575 (isomer 3);Psoralidin;BMS 433796;YO-01027 (GMP);BI-1408

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