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CAS No. : 145915-58-8
Biological Activity：CGP52411 (DAPH) is a high selective, potent, orally active and ATP-competitive EGFR inhibitor with an IC50 of 0.3 μM. CGP52411 blocks the toxic influx of Ca2+ ions into neuronal cells, and dramatic inhibits and reverses the formation of β-amyloid (Aβ42) fibril aggregates associated with Alzheimer’s disease.
Research Area：Cancer|Neurological Disease
Related Screening Libraries:Bioactive Compound Library Plus;Immunology/Inflammation Compound Library;JAK/STAT Compound Library;Kinase Inhibitor Library;Neuronal Signaling Compound Library;Protein Tyrosine Kinase Compound Library;Anti-Cancer Compound Library;Differentiation Inducing Compound Library;Anti-Alzheimer’s Disease Compound Library;Anti-Hepatitis C Virus Compound Library;Anti-Lung Cancer Compound Library;Anti-Pancreatic Cancer Compound Library;Neurodegenerative Disease-related Compound Library;Anti-Obesity Compound Library;Angiogenesis-Related Compound Library;Anti-Liver Cancer Compound Library ;Anti-Colorectal Cancer Compound Library ; Anti-Prostate Cancer Compound Library;Cancer Stem Cells Compound Library;
Related Small Molecules:β-Amyloid (13-27);NSC81111;Saikosaponin C;pp60 (v-SRC) Autophosphorylation Site, Phosphorylated;BMS-690514;β-Amyloid (1-42), (rat/mouse) (TFA);β-Amyloid (12-28) (TFA);Osimertinib-13C,d3;EGFR-IN-5;FGFR2-IN-3;BuChE-IN-5;Ginsenoside Rg1;MDR-1339;Genistein;Epertinib hydrochloride;β-Amyloid (11-22);UNC-CA359;Osimertinib mesylate;AV-412 free base;Nelipepimut-S;Falnidamol;20(S)-Ginsenoside Rg3;β-Amyloid (31-35);HER2-IN-6;PROTAC EGFR degrader 7;CHMFL-EGFR-202
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