For research use only. We do not sell to patients.


CAS No. : 1370544-73-2

Biological Activity:AX-024 is an orally available, first-in-class inhibitor of the TCR-Nck interaction that selectively inhibits TCR-triggered T cell activation with an IC50 ~1 nM. AX-024 modulates cell signaling by targeting SH3 domains. AX-024 has low-acute toxicity and high potency and selectivity, and strongly inhibit the production of IL-6, TNF-α, IFN-γ, IL-10 and IL-17A.

Research Area:Inflammation/Immunology

Targets:IFNAR|TNF Receptor|Interleukin Related

Related Screening Libraries:Bioactive Compound Library Plus;Apoptosis Compound Library;Immunology/Inflammation Compound Library;Kinase Inhibitor Library;Differentiation Inducing Compound Library;Pyroptosis Compound Library;Orally Active Compound Library;Angiogenesis-Related Compound Library;Rare Diseases Drug Library;Antidepressant Compound Library;Anti-Prostate Cancer Compound Library;Anti-Pulmonary Fibrosis Compound Library;Cancer Stem Cells Compound Library;

Related Small Molecules:Akt/NF-κB/JNK-IN-1;Cirsilineol;Ginsenoside F3;Perakizumab;PNRI-299;QNZ;CTX-471;Ac-YVAD-CHO;Sinulatumolin E;Deucravacitinib;Epobis;Mulberroside A;Sinulatumolin D;NFAT Transcription Factor Regulator-1;PDE4-IN-10;IL-17A antagonist 1;Kansuinine B;Ginsenoside Rc;TIC10;5(S)15(S)-DiHETE;IL-17A inhibitor 2;Teneliximab;Anti-Mouse IL-1b Antibody;Raleukin;Loganic acid 6′-O-β-D-glucoside;Ossirene;VGX-1027

Trending products:Recombinant Proteins  |  Bioactive Screening Libraries  |  Natural Products  |  Fluorescent Dye  |  PROTAC  |  Isotope-Labeled Compounds  |  Oligonucleotides

About Us:

  • MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use;
  • Structurally and synthetically diverse biologically active compounds;
  •  roduct quality is the key to our success and we take pride in offering only the highest-grade products.;
  • We provide HNMR, LC-MS, HPLC, stability testing and activity assays of our products to clients.;
  • Product identity, quality, purity and activity are assured by our robust quality control programs and procedures.;
  • Structurally and synthetically diverse biologically active compounds;

  • Customized order volume ranging from milligrams to kilograms scale;
  • We provide customer-oriented services. To explore more, please contact us at [email protected]. Our team will gladly assist you.

50K Diversity Library
Top Publications Citing Use of MCE Products
Recombinant Proteins