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13-Hydroxyisobakuchiol

CAS No. : 178765-49-6

Biological Activity：Hydroxyisobakuchiol (Delta3,2-Hydroxylbakuchiol), an analog of Bakuchiol (HY-N0235) isolated from Psoralea corylifolia (L.), is a potent monoamine transporter inhibitor. 13-Hydroxyisobakuchiol is more selective for the dopamine transporter (DAT) (IC₅₀=0.58 μM) and norepinephrine transporter (NET) (IC₅₀=0.69 μM) than for the serotonin transporter (SERT) (IC₅₀=312.02 μM). 13-Hydroxyisobakuchiol has the potential for the research of disorders such as Parkinson’s disease, depression, and cocaine addiction.

Research Area：Neurological Disease

Targets：Dopamine Transporter|Monoamine Transporter

Related Small Molecules:Diclofensine;Fipexide;hENT4-IN-1;Vanoxerine;SPD-473 citrate;GZ-793A;Diclofensine-d3 hydrochloride;Pseudoisocyanine iodide;Bisacodyl;AHN 1-055 hydrochloride;BMS-466442;Tesofensine;FFN511;Dasotraline hydrochloride;Nisoxetine hydrochloride;Valbenazine tosylate;DOV-216,303 Free Base;Radafaxine hydrochloride;GBR 12935

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