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Biological Activity：URAT1 inhibitor 2 is an orally active and potent URAT1 and CYP isozyme inhibitor, with IC50 values of 1.36 μM, 16.97 μM, 5.22 μM for URAT1-mediated 14C-UA uptake, CYP1A2 and CYP2C9, respectively. URAT1 inhibitor 2 is a promising drug candidate in the study of hyperuricemia and gout.
Related Small Molecules:Lesinurad;KPH2f;Epaminurad;Puliginurad;Benzarone;Xininurad;URAT1 inhibitor 1;Verinurad;Ruzinurad;URAT1 inhibitor 3
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Structurally and synthetically diverse biologically active compounds；
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