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Theaflavin 3,3′-digallate
CAS No. : 30462-35-2
Biological Activity:Theaflavin 3,3′-digallate (TF-3) is a potent Zika virus (ZIKV) protease inhibitor with an IC50 of 2.3 μM. Theaflavin 3,3′-digallat directly binds to ZIKVpro (Kd=8.86 µM) and inhibits ZIKV replication. Theaflavin 3,3′-digallat inhibits the activity of gp41 and NS2B-3 protease and has antiviral activity against HSV and HIV-1. Theaflavin 3,3′-digallate, the typical pigment in black tea, is a potent antitumor agent[2].
Research Area:Cancer|Infection
Targets:HSV|HIV|Virus Protease
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