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CAS No. : 1011557-82-6

Biological Activity:Tenovin-6, an analog of Tenovin-1 (HY-13423), is an activator of p53 transcriptional activity. Tenovin-6 inhibits the protein deacetylase activities of purified human SIRT1, SIRT2, and SIRT3 with IC50s of 21 μM, 10 μM, and 67 μM, respectively. Tenovin-6 also inhibits dihydroorotate dehydrogenase (DHODH)[2].

Research Area:Cancer

Targets:Autophagy|Dihydroorotate Dehydrogenase|Sirtuin|MDM-2/p53

Related Screening Libraries:Bioactive Compound Library Plus;Apoptosis Compound Library;Cell Cycle/DNA Damage Compound Library;Epigenetics Compound Library;Metabolism/Protease Compound Library;Histone Modification Research Compound Library;Anti-Cancer Compound Library;Autophagy Compound Library;Anti-Aging Compound Library;Antioxidant Compound Library;Reprogramming Compound Library;Oxygen Sensing Compound Library;Ferroptosis Compound Library;Pyroptosis Compound Library;Glutamine Metabolism Compound Library;Anti-Pancreatic Cancer Compound Library; Anti-Blood Cancer Compound Library;Anti-Cancer Metabolism Compound Library;Mitochondria-Targeted Compound Library;Transcription Factor-Targeted Library;Anti-Colorectal Cancer Compound Library ;

Related Small Molecules:PROTAC Sirt2 Degrader-1;SIRT1/2/3-IN-1;MDM2-p53-IN-15;Cambinol;P1788;JGB1741;MC-VC-PABC-SP 141;Nicotinamide-d4;p53 and MDM2 proteins-interaction-inhibitor (racemic);Navtemadlin;Sirtuin modulator 3;MD-224;PfDHODH-IN-2;Resveratrol;Mutant p53 modulator-1;MDM2/4-p53-IN-2;SRT 1720 Hydrochloride;PTC299;MX69;p-nitro-Pifithrin-α;RG7112;MMRi62;Anticancer agent 50;NSC59984;DHODH-IN-1;Pifithrin-β hydrobromide;Ivaltinostat formic;Sirtuin modulator 2;GEM-5

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