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TCS 21311

CAS No. : 1260181-14-3

Biological Activity：TCS 21311 (NIBR3049) is a potent, highly selective JAK3 inhibitor with an IC₅₀ of 8 nM, it displays >100-fold selectivity over JAK1, JAK2 and TYK2. TCS 21311 (NIBR3049) inhibits PKCα, PKCθ, and GSK3β with IC₅₀s of 13, 68, and 3 nM, respectively.

Research Area：Cancer

Targets：JAK|GSK-3|PKC

Related Small Molecules:AZ-3;TCS2002;[Ala107]MBP(104-118) TFA;JAK3/BTK-IN-1;BJE6-106;AR-A014418;Myelin Basic Protein;AT9283;Staurosporine;Benzene hexabromide;PKC-iota inhibitor 1;(E/Z)-Zotiraciclib;JAK-IN-10;Hypericin;Baricitinib-d3;Malantide;JAK3-IN-6;PKCiota-IN-2 formic;GSK 3 Inhibitor IX;Coumermycin A1;Deucravacitinib;Momelotinib-3,3,5,5-d4;SJ10542;Delgocitinib

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