For research use only. We do not sell to patients.

SM-324405

CAS No. : 677773-91-0

Biological Activity：SM-324405 is a TLR7 agonistic antedrug (EC₅₀ = 50 nM), with pEC₅₀ values of 7.3 and 6.6 for human TLR7 and Rat TLR7, respectively. SM-324405 is used for immunotherapy of allergic diseases. An antedrug is defined as a locally active compound that is designed to be rapidly metabolized to an inactive form upon entry into the circulation and prevents systemic toxicity by losing its agonistic activity in a plasmatic environment^[2]^[3].

Research Area：Inflammation/Immunology

Targets：Toll-like Receptor (TLR)

Related Screening Libraries:Bioactive Compound Library Plus;Immunology/Inflammation Compound Library;Small Molecule Immuno-Oncology Compound Library;Antioxidant Compound Library;Reprogramming Compound Library;Oxygen Sensing Compound Library;Pyroptosis Compound Library;

Related Small Molecules:C29;TMX-201;RS 09;ODN 20844;TLR7/8-IN-1;TLR8 agonist 5;Sulfo-ara-F-NMN;TLR7/8 antagonist 1;Gardiquimod;PF-4878691;Tri(TLR4-IN-C34-PEG2-amide-PEG1)-amide-C3-COOH;Pepinh-TRIF TFA;Afimetoran;Schaftoside;ODN 2088;CU-CPT22;UC-1V150;Diprovocim-X;CL264;MMG-11 quarterhydrate;CU-CPT 4a;TLR7/8 agonist 4;Enpatoran

About Us:

MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use；
Structurally and synthetically diverse biologically active compounds；
roduct quality is the key to our success and we take pride in offering only the highest-grade products.；
We provide HNMR, LC-MS, HPLC, stability testing and activity assays of our products to clients.；
Product identity, quality, purity and activity are assured by our robust quality control programs and procedures.；

Structurally and synthetically diverse biologically active compounds；

Customized order volume ranging from milligrams to kilograms scale；

We provide customer-oriented services. To explore more, please contact us at [email protected]. Our team will gladly assist you.

Top Publications Citing Use of MCE Products