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sEH inhibitor-2
Biological Activity：sEH inhibitor-2 (compound 5l) is an orally active (predicted percentage absorption: 71.2-88.4%) soluble epoxide hydrolase (sEH) inhibitor, with an IC50 of 0.9 nM. sEH inhibitor-2 can maintain epoxyeicosatrienoic acids (EETs) serum level in high concentrations. sEH inhibitor-2 can be used in study of cardiovascular protection.
Research Area：Cardiovascular Disease
Targets：Epoxide Hydrolase
Related Small Molecules:SWE101;sEH inhibitor-11;(Rac)-EC5026;GSK2256294A;BI-1935;UC-1728;CUDA;sEH/AChE-IN-4;sEH inhibitor-9;sEH/AChE-IN-3;sEH inhibitor-7;TPPU;sEH inhibitor-8;mEH-IN-1;Valpromide;ARM1;1-Cyclohexyl-3-dodecyl urea;sEH inhibitor-13;AUDA;sEH inhibitor-12;sEH inhibitor-4;Soluble epoxide hydrolase inhibitor;sEH inhibitor-1;sEH inhibitor-3;COX-2/sEH-IN-1;1,3-Dicyclohexylurea;AR-9281
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