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Regorafenib mesylate
CAS No. : 835621-08-4
Biological Activity：Regorafenib (BAY 73-4506) mesylate is an orally active and potent multi-targeted receptor tyrosine kinase inhibitor, with IC50 values of 13/4.2/46, 22, 7, 1.5 and 2.5 nM for VEGFR1/2/3, PDGFRβ, Kit, RET and Raf-1, respectively. Regorafenib mesylate shows very robust antitumor and antiangiogenic activity.
Research Area：Cancer
Targets：Autophagy|Raf|VEGFR|RET|c-Kit|FGFR|PDGFR
Related Small Molecules:(Z)-FeCP-oxindole;Avutometinib;VEGFR-2-IN-24;BMS-690514;PROTAC VEGFR-2 degrader-2;AZ 628;Henatinib;PI3K/VEGFR2-IN-1;c-Kit-IN-5-1;Flumatinib mesylate;IHMT-TRK-284;RET-IN-18;Ferulic acid-13C3;PDGFRα/FLT3-ITD-IN-2;FGFR-IN-7;PP58;Hydroxytanshinone IIA;Chiauranib;Foretinib;ZM323881 hydrochloride;Zeteletinib;FGFR3-IN-1;Pexidartinib;PTC299
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