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NAMPT inhibitor-linker 2
CAS No. : 2241014-82-2
Biological Activity：NAMPT inhibitor-linker 2 is a drug-linker conjugates for ADC, composed of an NAMPT inhibitor as a payload, and a linker. ADC-4 consists of an NAMPT inhibitor-linker 2 and an anti-c-Kit monoclonal antibody, exihibits potent activity against c-Kit expressing cell lines such as GIST-T1 and NCI-H526, with IC50s of <7 pM and 40 pM, respectively.
Research Area：Cancer
Targets：NAMPT|Drug-Linker Conjugates for ADC
Related Small Molecules:L-Asparagine-N-Fmoc,N-beta-trityl-15N2;Val-Cit-PAB-MMAF sodium;MC-VC-PABC-SP 141;Teglarinad chloride;Deruxtecan analog 2;PSMA-ALB-56;Gly3-VC-PAB-MMAE;MP-PEG8-Val-Lys-Gly-7-MAD-MDCPT;Tesirine;CB 300919;SPB;(Rac)-Lys-SMCC-DM1;VcMMAE;MC-Alkyl-Hydrazine Modified MMAF;Mc-MMAE;DGN549-L;MC-VA-PAB-Exatecan;GNE-617;MC-SN38;DBCO-(PEG2-VC-PAB-MMAE)2;DBCO-PEG4-MMAF;DM4-SPDP;SuO-Glu-Val-Cit-PAB-MMAE;MC-DOXHZN;Mal-PEG4-VC-PAB-DMEA-Seco-Duocarmycin SA;SPP-DM1
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