Metyrapone

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Metyrapone

CAS No. : 54-36-4

Biological Activity:Metyrapone (Su-4885) is a potent and orally active 11β-hydroxylase inhibitor and an autophagy activator, also inhibits the production of aldosterone. Metyrapone inhibits synthesis of endogenous adrenal corticosteroid, decreases glucocorticoid levels, and also affects behavior and emotion. In addition, Metyrapone increases the efficiency of autophagic process via downregulation of mTOR pathway, and interacts with Pseudomonas putida cytochrome P-450. Metyrapone can be used for researching Cushing’s syndrome and depression[2][3][4][5].

Research Area:Cancer|Endocrinology|Metabolic Disease|Neurological Disease

Targets:Autophagy|Endogenous Metabolite|Cytochrome P450

Related Screening Libraries:Drug Repurposing Compound Library Plus;FDA-Approved Drug Library Plus;FDA-Approved Drug Library Mini;Bioactive Compound Library Plus;Metabolism/Protease Compound Library;FDA-Approved Drug Library;Anti-Cancer Compound Library;Autophagy Compound Library;Anti-Aging Compound Library;Drug Repurposing Compound Library;Antioxidant Compound Library;Oxygen Sensing Compound Library;Endocrinology Compound Library;Anti-COVID-19 Compound Library;Endoplasmic Reticulum Stress Compound Library;Orally Active Compound Library;FDA Approved & Pharmacopeial Drug Library;Drug-Induced Liver Injury (DILI) Compound Library;Rare Diseases Drug Library;FDA-Approved Anticancer Drug Library;Human Metabolite Library;

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