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Metoprine
CAS No. : 7761-45-7
Biological Activity：Metoprine (BW 197U) is a potent histamine N-methyltransferase (HMT) inhibitor. Metoprine, a diaminopyrimidine derivative, can cross the blood-brain barrier and increase brain histamine levels by inhibiting HMT[2]. Metoprine is an antifolate and antitumor agent[3].
Research Area：Cancer|Neurological Disease
Targets：Histone Methyltransferase|Antifolate
Related Screening Libraries:Bioactive Compound Library Plus;Cell Cycle/DNA Damage Compound Library;Epigenetics Compound Library;Histone Modification Research Compound Library;Anti-Cancer Compound Library;CNS-Penetrant Compound Library;Anti-Aging Compound Library;Reprogramming Compound Library;Anti-Blood Cancer Compound Library;Anti-Cancer Metabolism Compound Library;Targeted Diversity Library;Human Metabolite Library;
Related Small Molecules:EEDi-5285;EZH2-IN-2;BIX-01294;SGC707;(S)-HH2853;G9a-IN-1;UNC4976;MS1943;OTS186935 hydrochloride;MS8815;(R)-HH2853;EPZ020411;Furamidine dihydrochloride;EZH2-IN-12;UNC0642;MU1656;Chaetocin;UNC0646;UNC0224;MRK-740;SMYD2-IN-1;PRMT5-IN-21;Sinefungin;MM-401;SETDB1-TTD-IN-1;Dot1L-IN-2
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