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IRAK4-IN-22
CAS No. : 2170694-05-8
Biological Activity：IRAK4-IN-22 (compound 18) is an orally active, potent and selective IRAK4 inhibitor with IC50 values of 3 and 17 nM for IRAK4 and TAK1, respectively. IRAK4-IN-21 effectively inhibits IL-23 production (IC50=0.10 µM) and can be used in studies of autoimmune diseases such as plaque psoriasis and psoriatic arthritis.
Research Area：Inflammation/Immunology
Targets：IRAK
Related Small Molecules:IRAK4-IN-8;Edecesertib;IRAK inhibitor 2;PROTAC IRAK4 degrader-3;IRAK inhibitor 6;GNE-2256;IRAK4-IN-14;PROTAC IRAK4 degrader-1;HG-12-6;JH-X-119-01;IRAK4-IN-19;IRAK4-IN-6;KTX-582;IRAK4-IN-11;HS271;IRAK-4 protein kinase inhibitor 2;PROTAC IRAK4 degrader-6;IRAK4-IN-17;Ginsenoside Rb1;Zabedosertib;IRAK4-IN-12;IRAK-1-4 Inhibitor I;IRAK4-IN-15;IRAK inhibitor 3;PROTAC IRAK4 degrader-7;KTX-955;Zimlovisertib;KTX-497
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