Ilorasertib

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Ilorasertib

CAS No. : 1227939-82-3

Biological Activity:Ilorasertib (ABT-348) is a potent, orally active and ATP-competitive aurora inhibitor with IC50s of116, 5, 1 nM for aurora A, aurora B, aurora C, respectively. Ilorasertib also is a potent VEGF, PDGF inhibitor. Ilorasertib has the potential for the research of acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS)[2].

Research Area:Cancer

Targets:VEGFR|Aurora Kinase|PDGFR

Related Small Molecules:(Z)-FeCP-oxindole;DB0614;VEGFR-2-IN-24;BMS-690514;AT9283;PROTAC VEGFR-2 degrader-2;Henatinib;PI3K/VEGFR2-IN-1;Flumatinib mesylate;IHMT-TRK-284;PDGFRα/FLT3-ITD-IN-2;PP58;Hydroxytanshinone IIA;Chiauranib;Foretinib;ZM323881 hydrochloride;Zeteletinib;PTC299;ENMD-2076 Tartrate;Aflibercept;SU5408;Barasertib-HQPA;MAZ51;R1530

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