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BIRT 377
CAS No. : 213211-10-0
Biological Activity:BIRT 377 is a potent amd orally bioavailable inhibitor of the interaction between intercellular adhesion molecule-1 (ICAM-1) and lymphocyte function-associated antigen-1 (LFA-1), with a Ki of 25.8 nM. BIRT 377 also inhibits the production of IL-2 in vivo. BIRT 377 can be used for researching inflammatory and immune disorders.
Research Area:Inflammation/Immunology
Targets:Integrin|Interleukin Related
Related Screening Libraries:Bioactive Compound Library Plus;Immunology/Inflammation Compound Library;Differentiation Inducing Compound Library;Cytoskeleton Compound Library;Orally Active Compound Library;Angiogenesis-Related Compound Library;
Related Small Molecules:AX-024;Ginsenoside F3;Perakizumab;GRGDSPK;Integrin Binding Peptide;PNRI-299;Cyclo(Arg-Gly-Asp-D-Phe-Cys);CTX-471;Ac-YVAD-CHO;Zaurategrast ethyl ester sulfate;Deucravacitinib;HSDVHK-NH2;Mulberroside A;NFAT Transcription Factor Regulator-1;IL-17A antagonist 1;Kansuinine B;Ginsenoside Rc;Lifitegrast sodium;TC-I 15;5(S)15(S)-DiHETE;α2β1 Integrin Ligand Peptide;Integrin modulator 1;Veltuzumab;GRGDSP TFA;IL-17A inhibitor 2;Anti-Mouse IL-1b Antibody;Raleukin;Ossirene
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